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From bronze to king, the road of advancement for scientific researchers (2) - Tutorial on the basic operation of cellular experiments

Sep 11,2023

From bronze to king, the road of advancement for scientific researchers (2) - Tutorial on the basic operation of cellular experiments

Cell culture is the most basic operation for cell experiments. Through cell culture, we can obtain a large number of cells, which can be used for further research on cell function and signalling pathways, so the quality of cell culture will directly affect the subsequent cell experiments and the accuracy of the results.
An active targeting approach for the treatment of osteosarcoma with nanodelivery systems

Sep 11,2023

An active targeting approach for the treatment of osteosarcoma with nanodelivery systems

Osteosarcoma is the most common in situ tumour of bone, accounting for approximately 35% of bone malignancies. The main symptoms of patients with osteosarcoma include restricted mobility, swelling, severe pain, and pathological fracture, and approximately 10-20% of patients have metastases at the time of their initial consultation. Conventional treatment includes early surgical resection and adjuvant chemotherapy, but a larger proportion of patients still respond poorly to treatment. The current first-line chemotherapeutic agents include adriamycin, cisplatin and methotrexate, which synergistically exert anti-tumour effects through different mechanisms of action, but due to the lack of selectivity of these agents and more pronounced systemic toxicity when applied in high doses, new therapeutic approaches need to be explored.
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Going with the Times Going with the Hometown

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Protein Immunoblotting - Immunohybridisation and Detection (below)

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Protein Immunoblotting - Immunohybridisation and Detection (above)

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Protein immunoblotting - protein transfer (below)

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Protein immunoblotting - protein transfer (above)

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Protein immunoblotting - electrophoresis (below)

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Protein immunoblotting - electrophoresis (above)

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Protein immunoblotting - preparation of gel matrices (below)

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