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Preclinical CRO

CDMO Services for Cell Therapy Products

Preclinical CRO

Pharma CRDMO
( Contract research, development and production )

Preclinical Animal Testing

R&D Pipeline
Gene Therapy

Establishment Of Disease Animal Models

Non-human primate experimental animal disease models

(1) Metabolic Abnormalities Disease Model
1. Spontaneous diabetes
2.Spontaneous hyperlipidemia
3.Hyperuricemia
4.Obesity
5. Alcoholic and non-alcoholic liver injury-hypertension, atherosclerosis
6. Hypercholesterolemia induced by high-fat diet
7. Type 2 diabetes and metabolic syndrome induced by food- and lifestyle
8. Type 1 diabetes mellitus induced by Streptozotocin (STZ)

(2)Joint and bone disease model
1. Osteoporosis induced by ovariectomy
2. Spontaneous rheumatoid arthritis
3. Surgically induced osteoarthritis (medial meniscus injury)
4. Skeletal defect model

(3）Ophthalmic disease models
1. Spontaneous macular degeneration
2. Induced macular degeneration
3. Glaucoma

(4)Central nervous system diseases
1.Parkinson's Disease (PD) -unilateral hemiplegia induced by MPTP
2.Alzheimer's Disease (AD)
3.Ischemic Stroke

Small animal (rat and mouse) disease models

No.	Type of disease system	Animal model
1	Digestive System Disease Models	Liver Cirrhosis Model Alcoholic fatty liver model Non-alcoholic fatty liver model
2	Respiratory Disease Models	Acute respiratory distress syndrome model Chronic Bronchitis Model Emphysema model
3	Cardiovascular System Disease Models	Myocardial Ischemia Model Myocardial Ischemia Reperfusion Model Hypertension model
4	Obstetric and Gynecological Diseases Models	Premature Ovarian Failure Model Spontaneous Miscarriage Model Polycystic ovary model
5	Neurological Diseases models	Stroke Models Cerebral Traumatic Brain Injury Spinal Cord Injury Models
6	Skeletal System Diseases models	Osteoarthritis model
7	Tumor Models	Subcutaneous Transplantation Tumor Model Orthotopic transplantation Tumor model Tumor Metastasis Model
8	Genome editing model	Knock out/Knock in Model

The disease model cases above are limited, please call us orcontact our customer service to consultation about more specific animal disease model details.