HUAREN MEDICAL TECHNOLOGY

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Preclinical CRO

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Preclinical CRO

CDMO Services for Cell Therapy Products

Preclinical CRO

Pharma CRDMO
( Contract research, development and production )

Preclinical Animal Testing

R&D Pipeline
Gene Therapy

Alteration And Modification Of Lead Compounds

Service Introduction

Pilot compounds are very important molecular structures in the process of drug design and development, and are the basis for subsequent research and development. Compound molecules with certain activity can be obtained through virtual screening methods, and the use of lead compound optimization methods can modify and replace the moieties of the obtained compound structures, thus obtaining compound molecules with higher activity. The basic idea of lead compound optimization is to analyze the binding mode of the compound with the drug target, to obtain the occupation of the compound in the active space, to analyze the interaction of the surrounding amino acids, and to carry out specific modifications and transformations of specific groups of the compound based on this information.