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HUAREN MEDICAL TECHNOLOGY

NEWS

17

2021-12

Warren Medical Experts Reveal Hidden Cancer Causes in the Bowel


Thomas F. Meyer, a consultant expert at Warren Medical Technology Group, recently published an article in Cancer Cell, a prestigious high-level academic journal, reviewing the progress of research related to colistin and cancer. Intestinal colonisation by colistin-producing bacteria is associated with colorectal cancer, and colistin shows a causal relationship in the mutational profile of human cancers. However, this only partially explains the phenomenon of cellular carcinogenesis, and does not adequately reveal that DNA damage leads to genomic mutations and chromosomal instability, which are the main factors of colistin-induced cancers.

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17

2021-12

What exactly is the secret weapon of Omicron (Omicron), the new mutant strain of New Crown?


According to the Tianjin Epidemic Prevention and Control Command on the 13th, the Tianjin Center for Disease Control and Prevention (TCDC) carried out whole genome sequencing and sequence analysis of respiratory specimens of asymptomatic infected persons with the new coronavirus imported from outside Tianjin on December 9, and after review by the Chinese Center for Disease Control and Prevention (CDC), the detection of the new coronavirus omnicorn variant strain (B.1.1.529 evolutionary branch) was confirmed. The infected person in Tianjin is an inbound closed-loop control person, and is currently under quarantine in a designated hospital for treatment. This is the first time that an omicron variant strain of Neocoronavirus has been detected in Mainland China, and on 15 December, there was a new case of asymptomatic infection associated with the importation of omicron from overseas in Guangzhou.

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30

2021-11

Hsf1 is a novel target for maintaining HSC adaptation and protein homeostasis


In vitro expansion of haematopoietic stem cells (HSC) has historically been a challenging process.Kruta et al. identified heat shock factor 1 (Hsf1) as a novel target for maintaining HSC fitness and protein homeostasis, not only under culture conditions, but also upon ageing.

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25

2021-11

New evidence for adult beta-cell neogenesis


In the present study, Gribben provided clear evidence of new islet cell formation in the pancreatic ducts of adult mice using improved genealogical tracking of mice and longer tracking times, and perhaps these data will put an end to the controversy over adult β-cell neogenesis. Any form of diabetes (type I, type II, or monogenic) is caused by insufficient β-cell insulin secretion. Replacement of β-cells by transplantation of pancreatic islets or stem cell-derived progenitor or β-like cells is an active treatment, but another approach being explored is to stimulate in vivo expansion of endogenous β-cells.The two main pathways for β-cell expansion are (i) replication of pre-existing β-cells (self-replication), and (ii) differentiation of progenitor/stem cells in the pancreatic ducts (de novo). The issue of β-cell neogenesis in adult mice has been controversial, with some lineage tracing studies showing neogenesis and others showing no neogenesis.

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15

2021-01

Discovery of a new CRISPR isoform: Cas7-11, a programmable RNA targeting tool


Researchers have identified a new type III-E CRISPR-Cas isoform consisting of a polypeptide with crRNA processing and sequence-specific RNA cleavage activity, providing a new RNA knockdown tool for mammalian cells with lower off-target effects than current technologies.

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