HUAREN MEDICAL TECHNOLOGY
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11
2023-09
Cell culture is the most basic operation for cell experiments. Through cell culture, we can obtain a large number of cells, which can be used for further research on cell function and signalling pathways, so the quality of cell culture will directly affect the subsequent cell experiments and the accuracy of the results.
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2023-09
An active targeting approach for the treatment of osteosarcoma with nanodelivery systems
Osteosarcoma is the most common in situ tumour of bone, accounting for approximately 35% of bone malignancies. The main symptoms of patients with osteosarcoma include restricted mobility, swelling, severe pain, and pathological fracture, and approximately 10-20% of patients have metastases at the time of their initial consultation. Conventional treatment includes early surgical resection and adjuvant chemotherapy, but a larger proportion of patients still respond poorly to treatment. The current first-line chemotherapeutic agents include adriamycin, cisplatin and methotrexate, which synergistically exert anti-tumour effects through different mechanisms of action, but due to the lack of selectivity of these agents and more pronounced systemic toxicity when applied in high doses, new therapeutic approaches need to be explored.
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2023-08
Principles of Transdermal Cell Therapy - TCR-T
Recently, Cell Reports Medicine, an internationally renowned journal, released the Phase I clinical research results of TAEST16001, the first TCR-T therapy product in China [1].TAEST16001 is used for the treatment of advanced soft-tissue sarcoma, which is a key step towards the clinical translation of ACT in the field of solid tumours, and once again ignited people's confidence in the treatment of solid tumours with TCR-T therapies. confidence in TCR-T therapy for solid tumours. In this issue, let's talk about the ins and outs of TCR-T therapy.
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2023-08
Principles of Cellular Immunotherapy - CAR-T
In the past decades, scientific research on the anti-tumour mechanism of immune cells has made rapid development, and Adoptive Cell Therapy (ACT) has become the most promising method to cure cancer.ACT therapy refers to the method of collecting the patient's blood, isolating the immune cells in vitro, and infusing them back into the patient's body through modification, proliferation, cultivation, and identification to achieve the purpose of treating cancer. ACT therapy mainly includes TILs, CAR-T, TCR-T, etc. CAR-T (Chimeric Antibody Therapy) is the most promising method to treat cancer.
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2023-08
Micro- and nanorobotics applied to the targeted transport of stem cells
With the rapid development of robotics technology, robots are more and more widely used in daily life, and they are also of great significance to the development and progress of society. With the development of nanotechnology, micro/nanorobot (micro/nanorobot) has gradually become a hotspot for research, and they can operate at the micron or even nanometer scale. Due to the small size of these robots, which are only at the micron or nano level, they can enter into more confined spaces and can also form clusters to work together to accomplish specific tasks.
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2023-08
New hydrogel induces endometrial regeneration
According to the data of "China Infertility Status Survey Report", the number of infertility patients in China has been increasing year by year, and by 2023 it will have exceeded 50 million, accounting for 12.5-15% of the population of childbearing age. Infertility refers to the situation that couples who have been living together for more than 1 year, have normal sex life and do not have any contraceptive measures, but still fail to get pregnant, which seriously affects the couple's relationship and family harmony [1]. Endometrial abnormality is one of the important factors leading to female infertility.
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