HUAREN MEDICAL TECHNOLOGY
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2023-07
Aspartame causes cancer? Are sugar substitutes still okay to eat?
Recently, a story about aspartame causing cancer hit the hot seat and caused a lot of buzz. The reason for this buzz is that the International Agency for Research on Cancer (IARC), which is part of the World Health Organisation (WHO), will likely announce in July that the artificial sweetener aspartame is "probably carcinogenic to humans", according to sources cited by Reuters. According to IARC's classification, aspartame would be classified in group 2b, which means that there is only a small amount of evidence to suggest that they may cause cancer, along with petrol, electromagnetic radiation and other carcinogens.
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2023-06
Western Blot (WB), the Chinese name for protein immunoblotting assay, is the most commonly used protein detection technique in molecular biology.WB separates protein samples according to molecular weight by polyacrylamide gel electrophoresis, and then transfers them to solid-phase carriers, where the size and content of the proteins are indicated by immunohybridisation with antibodies and by a chromogenic reaction to assess the expression of the proteins in the cells and tissues. The protein expression in cells and tissues can be assessed.
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2023-06
Threaded bolus method-preparation of MCAO model of cerebral ischemia/reperfusion
Ischaemic stroke/cerebral infarction poses a serious threat to human health and is the third leading cause of death and physical injury nationally and globally. The high morbidity, disability and mortality rates of stroke place a heavy burden on families and society. In order to effectively select drugs for the treatment of ischaemic stroke and to improve the cure and recovery rates, the establishment of a middle cerebral artery occlusion (MCAO) reperfusion model close to the human infarction has been a challenge for researchers, and the use of a stable animal model is one of the most important tools for the study of such diseases. This paper describes the whole process of making experimental animal models for studying cerebral ischemia-reperfusion in SD rats from the aspects of selection of experimental animals, selection of wire bolus materials, fabrication and processing of wire boluses, and the influence of the external environment and surgery, so as to provide researchers with a long-term stable model of cerebral ischemia-reperfusion in SD rats and ultimately to improve the success rate and feasibility of the experimental animal models.
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2023-06
Piezocatalysis - a dynamic therapeutic strategy for tumours
The treatment of malignant tumours has always been a great clinical challenge. The current treatment for solid tumours mainly includes surgery, radiotherapy and chemotherapy. However, there is still a high mortality rate and new treatment modalities need to be constantly explored. With the development of nanotechnology, nanomaterials are widely used in biomedical fields. Among various types of nanomaterials, piezoelectric nanomaterials, as a kind of catalyst, can convert mechanical energy into electrical energy under the effect of weak mechanical vibration. In recent years, the concept of piezoelectric catalysis has been introduced into tumour therapy.
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2023-06
Iron death and the feud over mesenchymal stem cell therapy
Iron death? What was your first thought? Did you think that iron also dies? If you think so, you are wrong, Iron death is a new type of regulated cell death, this unique mode of cell death is driven by iron-dependent phospholipid peroxidation, regulated by a variety of cellular metabolic events, and is involved in many signalling pathways related to disease development. Since the emergence of the term "iron death" in 2012, the research on iron death has been increasing exponentially in recent years, and has been awarded as the research hotspot of the National Natural Science Foundation of China for consecutive years. Today, I would like to talk about what iron death is, what diseases iron death plays an important role in, and whether mesenchymal stem cells, which are making a big splash in therapeutic fields, also have an impact on the disease damage caused by iron death. The MSCs have an unexpected effect on iron death-induced disease damage.
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2023-06
Not New Crown Not A-Flu, Little Known Deadly Virus - HMPV
Since this spring, a little-known virus, human metapneumovirus (HMPV), has been spreading in the United States, with infection rates soaring. Surveillance data from the CDC's National Respiratory and Enteric Virus Surveillance System (NREVSS) show that HMPV infections spiked to record levels from January to May this year (Figure 2).
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